Tyurin M.V., Orlova T.I., Tomilova O.G., Saveleva E.I., Kryukov V.Yu., Berestetskiy A.O. 2018. [Production of Cordyceps militaris metabolites in infected wax moth Galleria mellonella L. larvae] // Euroasian Entomological Journal. Vol.17. No.5: 373–377 [in Russian, with English summary].
Institute of Systematics and Ecology of Animals, Russian Academy of Sciences, Siberian Branch, Frunze Str. 11, Novosibirsk 630091 Russia.
Federal State Unitary Enterprise «Scientific Research Institute of Hygiene, Occupational Pathology and Human Ecology» art. Kapitolovo, build. № 93 Leningradskaya Oblast, g.p. Kuzmolovsky 188663 Russia.
All-Russian Research Institute of Plant Protection, Podbelskogo Str. 3, St.-Petersburg–Pushkin 196608 Russia.
ABSTRACT. This study examines accumulation dynamics of Cordyceps millitaris toxins in wax moth Galleria mellonella larvae after injection of fungal blastospores. At 3 and 4 days post infection average concentration of cordycepin was 244 ± 41 ng per 100 mg of dry mass of larvae. Accumulation of cordycepin was delayed one day in larvae, that were envenomated, by parasitoid Habrobracon hebetor (Say). Cordycepin concentration was correlated with hyphal bodies count in hemolymph, but only on tendency level (P > 0.07). The role of Cordyceps millitaris toxins in the development of mycoses was discussed.
KEY WORDS: Cordycepin, Cordyceps millitaris, Galleria mellonella, mycosis, fungal toxins.